Blog

Check out our new Pre-Seed YouTube Channel!

Come join us at our new Pre-Seed YouTube Channel http://www.youtube.com/user/PreSeed#p/a. We look forward to an ever growing library of fun product reviews and TTC information. Please be sure and share any helpful links with us!

Also, stay tuned for our Pre-Seed user video contest coming up soon. Get those creative vibes flowing. We will have two categories of winners including the most humorous and the most heartfelt/inspiring…so stay tuned!

Blessings - Dr. E

YouTube User Review

We thought you might enjoy this informative Pre~Seed user review http://www.youtube.com/watch?v=IYX13ZCWgfo! In fact, we had so much fun watching it, we have decided to do a video contest in the fall! We will have categories for the most “heartfelt” and one for the most humorous Pre~Seed User stories. So stay tuned for more info!

Keep enjoying your summer!

New Study on Long Term Impact of Infertility in Men

A recent study (Fisher et al., Fertil Steril 7.2010) evaluated men's view of parenthood, as well as the quality of intimate relationships and life, five years after a diagnosis of male factor infertility. Most men in the study became fathers (87%) during the five-year time and most of these were thru assisted reproduction (3% adoption, 17% by spontaneous conception). Although, it is important to note that only 40% of men contacted, completed the survey.

This study found that some of our assumptions about men and fertility may not be true. Specifically, 84% of men said that becoming a parent was as important to them as it was to their female partners. An assumption is often made that fatherhood is not as important to men, as being a mother is to women.

These men also felt no more criticism or blame from their wives than did normal fertile men, suggesting that the assumption that women become resentful of infertile husbands over time, may not be true. In fact surprisingly, 100% of the men were in the same relationship that they had been in when diagnosed as infertile five years before (although only 40% of men completed the survey). Several other studies have found increased divorced rates among infertile couple, so this was good news for TTC couples.

Only 10% of the men equated their masculinity with fatherhood, which is also good news! The study did find that although physical health was equal between all men in the study, the men who never became fathers had lower mental health scores and tended to worry more than did men who ended up with children during the five years the study evaluated.

Studies such as this on the impact of fertility on men are few and far between. We were happy to see this data and have some light shed on some of the assumptions we al have about men and couples during infertility!

Remember the more enjoyable and stimulating intercourse is for the male partner, the higher the normal sperm counts he can make! So keep enjoying “baby-making” with Pre~Seed!

Pre~Seed in Special USA Today Report on Pregnancy Wellness!

You can view the special third edition report on Pregnancy Wellness in USA Today that came out last week! http://doc.mediaplanet.com/all_projects/5189.pdf.

This report helped spread the word that everyday vaginal lubricants can harm sperm and should not be used when trying to conceive. Pre~Seed and Dr. E added colorful features to the pre-conception section!

We were happy to see the great information this report provided for all moms to be!

How Soon After Semen Sample Collection Should Sperm Analysis be Done?

A recent study by Griffin et al. (ASRM 2009) looked at how long a semen sample could sit before being evaluated without adverse impact on sperm swimming (motility).  A total of 47 semen specimens were analyzed at 0, 2, 4 or 12 hrs from collection. Time 0 was on average 31 minutes after collection. The total percent motile sperm of the specimens and the rapidly moving percent did not significantly change comparing time 0 to 2 hours. Though, motility began declining at 4 hours with significant differences in total and rapid progression when compared to time 0. The authors concluded that semen analysis could be performed within 2 hours without compromising results, or stating a false decline in motility. Ask for your testing lab to write down the time your semen sample was evaluated so that you know if they are seeing any problems with motility due to poorer sperm quality or just poor testing techniques.  Also, always remember if you ever have a poor quality sperm test, have the test repeated within 30 days to verify the test results!  Also be sure and use Pre~Seed to provide slippery fun during collection. The more relaxed and enjoyable the collection , the more and the better, quality sperm can be produced.
Blessings - Dr. E

Enjoy Pre~Seed’s Updated Website!

Check out our updated Pre~Seed website! http://preseed.com/index.html.
It is easy to check our exciting references to Pre~Seed or Dr. E’s research in the news http://preseed.com/news.html.
Review all the medical studies done on Pre~Seed http://preseed.com/clinical-studies.html.
And read what users and physicians are saying about the product http://preseed.com/users-stories.html and http://preseed.com/healthcare.html.
We hope you enjoy it as much as we do!

New Independent Study Finds Pre~Seed Formula to be the Safest Lubricant on Tissues

A new study presented at the International Microbicides Conference in Pittsburgh http://microbicides2010.org/files/LubesDezzuttiAbstract.pdf evaluated the safety of several lubricants on different tissues, including uterine and cervical tissues. Investigators evaluated six products including: Astroglide, Elbow Grease, ID Glide, KY Jelly, Wet Platinum and PRÉ (made from the same formula as Pre~Seed). PRÉ alone was isotonic (same salt concentration as the body’s cells). Whereas the other water soluble lubricants contained higher amounts of dissolved salts compared to what is normally found in cells. As a result, these products had toxic effects on cells and tissues. “Some of the lubricants caused significant portions of the epithelium — the layer of cells that serves as a protective barrier — to be stripped away” according to Charlene Dezzutti, Ph.D., from the University of Pittsburgh and Magee-Womens Research Institute, who led the study for the Microbicide Trials Network. PRÉ and Wet Platinum were the safest lubricants in the studies, while Astroglide was the most toxic to cells, and KY Jelly had the worst effect on the good bacteria, essentially wiping them out. PRÉ was the only water-based lubricant that was isotonic and did not disrupt the tissues.

An amazing story!

Dear Friends, We have been going through preseed.com to update it (coming soon!), and this story is just so amazing it bears a second posting here

Dr. E

Dear Pre Seed, I have meant to write this letter for over a year now. So, here is our story… My wife and I tried to conceive for seven (yes seven!) years and spent over $35,000.00 at a fertility clinic, with no results. A very sad and emotionally draining experience to say the least. We just accepted that we may never be able to conceive our own children so we then decided to adopt a baby girl from China. We went through all of the classes, meetings, paperwork, background checks, and paid out lots more money so we could realize our dream of being parents. We were finally given a “log in date” of December of 2006. We were originally told it should only take 12 to 14 months from that date until we get pick up our daughter in China.

As of today’s date 8/18/09 we have still heard nothing from China… One evening almost two years ago I was watching television and a news anchor mentioned how some people were successfully conceiving using some sort of kit. I went upstairs, logged on to the Internet and began my research. I guess we just assumed that the doctors were giving all the credible methods we could use. I soon came across your wonderful product as well as the book “Taking Charge of Your Fertility”. I immediately ordered the book and read it in three days (Yes my wife thought I was a bit nuts). I then ordered Pre Seed and we began charting. Honestly, we were happy to have found another method that was very low stress, natural, and relatively inexpensive, but I don’t think we truly believed it would work.

Well, it did work, and it worked after only three months of trying. I will NEVER forget coming home to my wife waiting at the door with a little plastic thing that said “Pregnant”! Nothing had even said this once in seven years, and there it was. She started crying and I did too. Then, because we are both over forty, we decided to not get too excited because we are very aware of the risks. We couldn’t help it though. Something actually said PREGNANT! We were overjoyed.

The delivery of our son went as close to perfectly as one could hope. It went so quickly there wasn’t enough time left to administer any pain killers for my wife! Yeah, she’s a tough cookie. Our son just turned one year old on July 28th 2009, and he is the joy of our lives. I have told so many people about what worked for us…

Gratefully yours,
Frank, Jane and Frankie G

Look what Dr. Niederberger has to say about Pre~Seed!

Look what Dr. Craig Niederberger at the University of Illinois, Chicago has to say about Pre~Seed! http://www.maledoc.com/blog/2010/05/24/lube

Dr. Niederberger is a leading expert and author on male reproduction. http://www3.cambridge.org/us/catalogue/catalogue.asp?isbn=9780521872898

His blog is a great resource, with accurate information for the trying-to-conceive couple.

“Great News on CVS! Pre~Seed is such a wonderful product” – DL

Thanks to ALL of you who have written to tell us how excited you are to have Pre~Seed in your local CVS/pharmacy! We are continually adding to our list of independent pharmacies, shops and clinics that carry Pre~Seed, so be sure and check out our other locations at where-to-buy.html.

Also be sure and follow us at Twitter to see our new updated page! http://twitter.com/PreSeedBaby

Survey of Pre~Seed Use for Women with Poor Quality Cervical Fluids

134 people completed over 30 detailed questions in a self-reporting, opt-in internet, survey. Women were recruited through social media and chat room sites. Data are not a clinical study or necessarily reflective of the broader population. An emphasis of this survey was learning more about women who used Pre~Seed specifically because of poor quality cervical fluids/mucus.

Trying-to-conceive women, in our survey, used Pre~Seed because of inadequate vaginal secretions, including cervical fluids, based on the following personal needs:

• 44% to relieve dryness and discomfort during intercourse
• 35% to supplement low quality cervical fluid
• 52% to supplement too little quantity of cervical fluid
• A total of 87 women used Pre~Seed for poor quality cervical fluids with 81% of these women saying it increased their cervical fluid quality; and 64% saying it improved their cervical fluid quantity.
• 58% of women who took this survey, became pregnant while using Pre~Seed
  Of women with poor quality cervical fluid, 57% became pregnant while using Pre-Seed
• 75% of women used Pre~Seed twice or more during their fertile time
• 30% of users became pregnant the first time they used Pre~Seed
• 15% the second time and 10% after 4 or more cycles
• 93% of users applied Pre~Seed inside the vagina
• 57% of users had been trying to conceive for 7 or more months before using Pre~Seed
• 40% of babies were a boy
• 38% of babies were a girl
• 20% of first pregnancies were lost (consistent with the 25-38% of all first trimester pregnancies lost in the general population)
• There were no multiple pregnancies in this group of survey responders

These results support the value of Pre~Seed to relieve dryness and supplement vaginal secretions involved in reproduction, including cervical fluids.

This is the third survey we have done in the past 7 years showing no gender differences in pregnancy outcomes for women using Pre~Seed.

Almost 1/3 of users became pregnant the first time they used Pre~Seed , even though a majority of users had been trying to conceive for more than half a year prior to using it.

Pre~Seed, coming to a CVS/pharmacy® near you!

Pre~Seed will be available in all CVS/pharmacy® stores this May! If you don’t see it stocked on the shelf yet, be sure to ask the store clerk or pharmacist for assistance in finding it. Be sure and tell your community this exciting news! Blessings- Dr. E

Cute Video!

“Check out this very cute video on an “Ovulation Celebration”! But be careful, it is enough to get you dancing at work and keep you there till baby-dancing time ”http://www.early-pregnancy-tests.com/ovulation-celebration-video.html

Cheers-~Dr. E

Declining Fertility with Age in Men

Declining fertility with age is not just a female issue. We all know about the increased risks of infertility or birth defects in older women who want to have a child, and are aware that these risks are due to chromosome changes in the egg that occur as women age.

However, as with most things reproductive, the medical community has lagged far behind in evaluating the effect of aging in men on sperm quality. Several recent studies have begun to paint a picture of aging of the male reproductive tract which is very similar to that seen in women.

Specifically, in a study of 2,000 couples (Hassan & Killick, Fertility & Sterility; June, 2003) men that were over 45 years of age had a five-fold increase in time to pregnancy for their partners (how long it took them to become pregnant) as compared to younger men. This effect was seen even after taking into account the variables of their wife’s age, how often they had intercourse and whether or not they had fertility adverse life styles (smoking, drinking etc..). Even older men who had very young wives (<25 yrs of age) had a four-fold increase in time to pregnancy.

In this study, 57% of these 2,000 unselected couples became pregnant within 3 months of trying to conceive, and 81% after 1 year. The average time to pregnancy increased from 7 months in men that were 25 years of age or younger, to 37 months in men that were over 45 years of age.

Other work suggests that similar to the changes seen in women, these delays in fertility may be due to DNA or chromosomal abnormalities in the sperm of older men. Singh et al (Fertility & Sterility, Dec 2003) found that the DNA of sperm in men ages 36-57 had far more breakage in the strands than did sperm from men ages 20-35. These strand breaks have been associated with infertility, early embryo losses, miscarriages and even birth defects or cancer in children.

Another study (Sloter et al., Fertility & Sterility April, 2004) also showed age related increases in the number of sperm with broken or damaged DNA for men, especially sperm with structural chromosomal abnormalities. This study suggested that these changes may be due to environmental toxin damage, or a loss of internal antioxidants in semen in aging individuals.

What can be done to help the chances of conceiving for older men?

Be sure and have a sperm chromatin assay done in addition to a normal semen analysis (visit http:// www.scsadiagnostics.com/ to learn more), so that you know if sperm DNA damage is present. I highly recommend this test for older men, especially because many older “dads-to-be” are on medications which may cause DNA strand breaks (e.g. antidepressants, cholesterol lowering drugs etc…).

When providing a semen sample for testing or for clinical procedures, use Pre~Seed^® as a sperm-friendly lubricant to help make semen sample collection more pleasant. This is important because the more enjoyable ejaculation is, the more normal sperm a man can produce for these samples!

There is also a growing body of evidence that vitamins with antioxidants help men with low fertility. Numerous studies have found that infertile men do not make enough of their own antioxidants in their semen to protect sperm on their journey at ejaculation and through the cervix. INGfertility^® did a study on FertilAid vitamins and found that this antioxidant containing fertility vitamin increased total motile sperm counts for some men. I do recommend that all TTC men take a fertility vitamins while TTC.

Make sure you have intercourse timed with ovulation to optimize the chances of sperm and egg meeting. Ovulation prediction tests, as well as tracking cervical mucus quality are effective ways to know when to get busy “baby-making”. Having intercourse every other day during your fertile window, up to your first day of “dry” (or less) cervical mucus, will make sure you cover the bases.

Vaginal dryness and a lack of secretions during your fertile window makes intercourse uncomfortable and can interfere with fertility. Supplementing your secretions with Pre~Seed^® makes “baby-making” more fun. Better feeling intercourse can increase sperm production! So take that time for at least one session during your fertile window to have “Gourmet Sex”—the long, relaxed, “we love each other” kind!

Blessings~ Dr. E